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🚨The White House just launched the Genesis Mission — a Manhattan Project for AI
The Department of Energy will build a national AI platform on top of U.S. supercomputers and federal science data, train scientific foundation models, and run AI agents + robotic labs to automate experiments in biotech, critical materials, nuclear fission/fusion, space, quantum, and semiconductors.
Let’s unpack what this order actually builds, and how it could rewire the AI, energy, and science landscape over the next decade:

1/ At the core is a new American Science and Security Platform.
DOE is ordered to turn the national lab system into an integrated stack that provides:
• HPC for large-scale model training, simulation, inference
• Domain foundation models across physics, materials, bio, energy
• AI agents to explore design spaces, evaluate experiments, automate workflows
• Robotic/automated labs + production tools for AI-directed experiments and manufacturing
National-scale AI scientist + AI lab tech as infrastructure.

2/ The targets are very explicit and very strategic.
Within 60 days, DOE has to propose at least 20 “national challenges” in:
• advanced manufacturing
• biotechnology
• critical materials
• nuclear fission & fusion
• quantum information science
• semiconductors & microelectronics
This is about energy dominance, supply chains, and defense.

3/ The timelines are aggressive enough to matter:
• 60 days → list of challenges
• 90 days → full inventory of federal compute/network/storage for Genesis
• 120 days → initial model + data assets, plus a plan to ingest more datasets (other agencies, academia, private sector)
• 240 days → map all robotic labs and automated facilities across national labs
• 270 days → demonstrate initial operating capability on at least one challenge
Goal: A Functioning AI-for-science loop online in <9 months.

4/ This also formalizes a federal AI stack parallel to the commercial one.
The order tells DOE and the White House science office to:
• align agency AI programs and datasets onto this platform
• run joint funding calls and prize programs
• build partnership frameworks with external players (co-dev agreements, user facilities, data/model sharing, IP rules)
Nvidia, OpenAI, Anthropic, xAI, Google, the clouds, biotech & chip companies are now potential suppliers and co-developers for a DOE AI system

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