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Major BioAI advance on designing therapeutic peptides:
PepMimic beat a leading method in overall performance on many tests.
✅ It designed 384 small protein pieces for five disease targets. About 8% stuck to their targets very strongly, and 26 had exceptionally strong stickiness. That is far better than picking at random.
✅ It could also copy other AI-made binders for two targets, working about 14% of the time overall.
✅ In mice, selected pieces homed in on tumors very well: about 9 times more in tumors with PD-L1 and about 16 times more in tumors with TROP2.
✅Overall, its success rate was tens of thousands of times higher than old-style random screening.
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