Physical activity and risk of Alzheimer's disease. In older adults (mean age 72) with elevated Aβ amyloid, 5,000-7,500 steps/day (<-a plateau) were associated with less Tau accumulation, improved cognition @NatureMedicine

In cognitively unimpaired individuals, cognitive decline was delayed an average of 3 years for participants with 3,000-5,000 steps/day, and 7 years in those who walked 5,000-7,500 steps/day