No matter how old you are, soon you’ll look like you’re 20-25. Below is proof that we’re making progress toward it. Scientists at NYU School of Medicine have uncovered a key cause of aging skin, and how to reverse it, at least in mice. They discovered that capillary associated macrophages (CAMs), immune cells that maintain tiny blood vessels, decline with age, leading to poorer blood flow and slower healing. Using live imaging and genetic tools, researchers watched this happen in real time, showing how microvascular repair falters as macrophages vanish. Then came the breakthrough, a short growth factor treatment (CSF1–Fc) boosted macrophage renewal, restoring microvascular repair and blood flow in aged skin. ! Human samples revealed the same age linked macrophage loss, hinting that a similar rejuvenation might work in people. In short - aging skin may be partially reversible, not by stretching or resurfacing it, but by repopulating its microscopic immune vascular network.